Cardiovascular Physiology and Pathophysiology
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2022

Bozoglu T, Lee S, Ziegler T, Jurisch V, Maas S, Baehr A, Hinkel R, Hoenig A, Hariharan A, Kim CI, Decker S, Sami H, Koppara T, Oellinger R, Müller OJ, Frank D, Megens R, Nelson P, Weber C, Schnieke A, Sperandio M, Santamaria G, Rad R, Moretti A, Laugwitz KL, Soehnlein O, Ogris M, Kupatt C. (2022) . Endothelial Retargeting of AAV9 In Vivo. Adv Sci (Weinh). 2022 Jan 12:e2103867. doi: 10.1002/advs.202103867. Online ahead of print. PMID: 35023328

2021

Elhag S, Stremmel C, Zehrer A, Plocke J, Hennel R, Keuper M, Knabe C, Winterhalter J, Gölling V, Tomas L, Weinberger T, Fischer M, Liu L, Wagner F, Lorenz M, Stark K, Häcker H, Schmidt-Supprian M, Völker U, Jastroch M, Lauber K, Straub T, Walzog B, Hammer E, Schulz C. (2021) Differences in Cell-Intrinsic Inflammatory Programs of Yolk Sac and Bone Marrow Macrophages. Cells. 2021 Dec 17;10(12):3564. doi: 10.3390/cells10123564. PMID: 34944072

Weckbach LT, Schweizer L, Kraechan A, Bieber S, Ishikawa-Ankerhold H, Hausleiter J, Massberg S, Straub T, Klingel K, Grabmaier U, Zwiebel M, Mann M, Schulz C; EMB Study Group (2021) Association of Complement and MAPK Activation With SARS-CoV-2-Associated Myocardial Inflammation. JAMA Cardiol. 2021 Dec 15. doi: 10.1001/jamacardio.2021.5133. Online ahead of print. PMID: 34910083

Elisabeth Deindl and Paul H. A. Quax,(2021) Arteriogenesis and Therapeutic Angiogenesis—An Update. Int. J. Mol. Sci. 2021, 22, 13244. https://doi.org/10.3390/ijms222413244 (Editorial)

Kübler M, Götz P, Braumandl A, Beck S, Ishikawa-Ankerhold H, Deindl E. (2021) Impact of C57BL/6J and SV-129 Mouse Strain Differences on Ischemia-Induced Postnatal Angiogenesis and the Associated Leukocyte Infiltration in a Murine Hindlimb Model of Ischemia. Int J Mol Sci. 2021 Oct 30;22(21):11795. doi: 10.3390/ijms222111795.
PMID: 34769229

Holtkamp SJ, Ince LM, Barnoud C, Schmitt MT, Sinturel F, Pilorz V, Pick R, Jemelin S, Mühlstädt M, Boehncke WH, Weber J, Laubender D, Philippou-Massier J, Chen CS, Holtermann L, Vestweber D, Sperandio M, Schraml BU, Halin C, Dibner C, Oster H, Renkawitz J, Scheiermann C. (2021) Circadian clocks guide dendritic cells into skin lymphatics.
Nat Immunol. 2021 Oct 18. doi: 10.1038/s41590-021-01040-x. Online ahead of print.
PMID: 34663979

Lasch, M., Vladymyrov, M., van den Heuvel, D., Götz, P., Deindl, E., Ishikawa-Ankerhold, H. (2021)
Multiphoton Intravital Imaging for Monitoring Leukocyte Recruitment during Arteriogenesis in a Murine Hindlimb
Model. J. Vis. Exp. (175), e62969, doi:10.3791/62969

Bader A, Gao J, Rivière T, Schmid B, Walzog B, Maier-Begandt D.(2021) Molecular Insights Into Neutrophil Biology From the Zebrafish Perspective: Lessons From CD18 Deficiency. Front Immunol. 2021 Sep 7;12:677994. doi: 10.3389/fimmu.2021.677994. eCollection 2021. PMID: 34557186

Salei N, Ji X, Pakalniškytė D, Kuentzel V, Rambichler S, Li N, Moser M, Steiger K, Buch T, Anders HJ, Schraml BU. (2021)
Selective depletion of a CD64-expressing phagocyte subset mediates protection against toxic kidney injury and failure.  Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2022311118. doi: 10.1073/pnas.2022311118. PMID: 34518373

Kübler M, Beck S, Peffenköver LL, Götz P, Ishikawa-Ankerhold H, Preissner KT, Fischer S, Lasch M, Deindl E. (2021) The Absence of Extracellular Cold-Inducible RNA-Binding Protein (eCIRP) Promotes Pro-Angiogenic Microenvironmental Conditions and Angiogenesis in Muscle Tissue Ischemia. Int J Mol Sci. 2021 Aug 31;22(17):9484. doi: 10.3390/ijms22179484. PMID: 34502391

Bromberger T, Klapproth S, Rohwedder I, Weber J, Pick R, Mittmann L, Min-Weißenhorn SJ, Reichel CA, Scheiermann C, Sperandio M, Moser M. (2021) Binding of Rap1 and Riam to Talin1 Fine-Tune β2 Integrin Activity During Leukocyte Trafficking. Front Immunol. 2021 Aug 19;12:702345. doi: 10.3389/fimmu.2021.702345. eCollection 2021.
PMID: 34489950 [Projects A01, B01, B03, B09E and Z03]

Arts JJ, Mahlandt EK, Grönloh M, Schimmel L, Noordstra I, Gordon E, van Steen AC, Tol S, Walzog B, van Rijssel J, Nolte MA, Postma M, Khuon S, Heddleston JM, Wait E, Chew TL, Winter M, Montanez E, Goedhart J, van Buul JD. (2021) Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration. Elife. 2021 Aug 25;10:e66074. doi: 10.7554/eLife.66074. Online ahead of print. PMID: 34431475

Silvia Fischer and Elisabeth Deindl (2021) Characterization of RNA in Extracellular Vesicles. Appl. Sci. 2021, 11, 7520. https://doi.org/10.3390/app11167520. Review

Yang WH, Westman JS, Heithoff DM, Sperandio M, Cho JW, Mahan MJ, Marth JD. (2021) Neu3 neuraminidase induction triggers intestinal inflammation and colitis in a model of recurrent human food-poisoning. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2100937118. doi: 10.1073/pnas.2100937118. PMID: 34266954

Hinkel R, Batkai S, Bähr A, Bozoglu T, Straub S, Borchert T, Viereck J, Howe A, Hornaschewitz N, Oberberger L, Jurisch V, Kozlik-Feldmann R, Freudenthal F, Ziegler T, Weber C, Sperandio M, Engelhardt S, Laugwitz KL, Moretti A, Klymiuk N, Thum T, Kupatt C (2021) AntimiR-132 Attenuates Myocardial Hypertrophy in an Animal Model of Percutaneous Aortic Constriction. J Am Coll Cardiol. 2021 Jun 15;77(23):2923-2935. doi: 10.1016/j.jacc.2021.04.028. PMID: 34112319

Chen CS, Weber J, Holtkamp SJ, Ince LM, de Juan A, Wang C, Lutes L, Barnoud C, Kizil B, Hergenhan SM, Salvermoser J, Lasch M, Deindl E, Schraml B, Baumjohann D, Scheiermann C. (2021) Loss of direct adrenergic innervation after peripheral nerve injury causes lymph node expansion through IFN-γ. J Exp Med. 2021 Aug 2;218(8):e20202377. doi: 10.1084/jem.20202377. Epub 2021 Jun 4. PMID: 34086056

Götz P, Braumandl A, Kübler M, Kumaraswami K, Ishikawa-Ankerhold H, Lasch M, Deindl E. (2021) C3 Deficiency Leads to Increased Angiogenesis and Elevated Pro-Angiogenic Leukocyte Recruitment in Ischemic Muscle Tissue. Int J Mol Sci. 2021 May 28;22(11):5800. doi: 10.3390/ijms22115800. PMID: 34071589

Henneke P, Kierdorf K, Hall LJ, Sperandio M, Hornef M. (2021) Perinatal development of innate immune topology. Elife. 2021 May 25;10:e67793. doi: 10.7554/eLife.67793. PMID: 34032570 Review

Uhl B, A Mittmann L, Dominik J, Hennel R, Smiljanov B, Haring F, B Schaubächer J, Braun C, Padovan L, Pick R, Canis M, Schulz C, Mack M, Gutjahr E, Sinn P, Heil J, Steiger K, Kanse SM, Weichert W, Sperandio M, Lauber K, Krombach F, Reichel CA. (2021) uPA-PAI-1 heteromerization promotes breast cancer progression by attracting tumorigenic neutrophils. EMBO Mol Med. 2021 May 16:e13110. doi: 10.15252/emmm.202013110. Online ahead of print.PMID: 33998175

Morikis VA, Hernandez AA, Magnani JL, Sperandio M, Simon SI. (2021) Targeting Neutrophil Adhesive Events to Address Vaso-Occlusive Crisis in Sickle Cell Patients. Front Immunol. 2021 Apr 28;12:663886. doi: 10.3389/fimmu.2021.663886. eCollection 2021. PMID: 33995392 Review

Stutte S, Ruf J, Kugler I, Ishikawa-Ankerhold H, Parzefall A, Marconi P, Maeda T, Kaisho T, Krug A, Popper B, Lauterbach H, Colonna M, von Andrian U, Brocker T. (2021) Type I interferon mediated induction of somatostatin leads to suppression of ghrelin and appetite thereby promoting viral immunity in mice. Brain Behav Immun. 2021 Apr 22:S0889-1591(21)00176-8. doi: 10.1016/j.bbi.2021.04.018. Online ahead of print.
PMID: 33895286

Immler R, Nadolni W, Bertsch A, Morikis V, Rohwedder I, Masgrau-Alsina S, Schroll T, Yevtushenko A, Soehnlein O, Moser M, Gudermann T, Barnea ER, Rehberg M, Simon SI, Zierler S, Pruenster M, Sperandio M. (2021) The voltage-gated potassium channel KV1.3 regulates neutrophil recruitment during inflammation. Cardiovasc Res. 2021 Apr 21:cvab133. doi: 10.1093/cvr/cvab133. Online ahead of print.
PMID: 33881519

Abdel Rahman F, d'Almeida S, Zhang T, Asadi M, Bozoglu T, Bongiovanni D, von Scheidt M, Dietzel S, Schwedhelm E, Hinkel R, Laugwitz KL, Kupatt C, Ziegler T. (2021) Sphingosine-1-Phosphate Attenuates Lipopolysaccharide-Induced Pericyte Loss via Activation of Rho-A and MRTF-A. Thromb Haemost. 2021 Mar;121(3):341-350. doi: 10.1055/s-0040-1716844. Epub 2020 Oct 4. PMID: 33011963

Matthias Kübler, Sebastian Beck, Silvia Fischer, Philipp Götz, Konda Kumaraswami, Hellen Ishikawa-Ankerhold, Manuel Lasch, and Elisabeth Deindl (2021). Absence of Cold-Inducible RNA-Binding Protein (CIRP) Promotes Angiogenesis and Regeneration of Ischemic Tissue by Inducing M2-Like Macrophage Polarization. Biomedicines 2021, 9, 395. https://doi.org/10.3390/biomedicines9040395

Nadolni W, Immler R, Hoelting K, Fraticelli M, Ripphahn M, Rothmiller S, Matsushita M, Boekhoff I, Gudermann T, Sperandio M and Zierler S. (2021). TRPM7 Kinase is Essential for Neutrophil Recruitment and Function via Regulation of Akt/mTOR Signaling. Front. Immunol. 11:606893. doi: 10.3389/fimmu.2020.606893

Andreas Margraf, Markus Sperandio (2021). Leukocyte Trafficking and Hemostasis in the Mouse Fetus in vivo: A Practical Guide. Front Cell Dev Biol. Jan 21;8:632297. doi: 10.3389/fcell.2020.632297. eCollection 2020.

Papaioannou, NE, Salei N, Rambichler S, Ravi K, Popovic J, Küntzel V, Lehmann CHK, Fiancette R, Salvermoser J, Gajdasik DW, Mettler R, Messerer D, Carrelha J, Ohnmacht C, Haller D, Stumm R, Straub T, Jacobsen SEW, Schulz C, Withers DR, Schotta G, Dudziak D, Schraml BU. (2021). Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice. Nature Communications 21, 464.

Dudeck J, Kotrba J, Immler R, Hoffmann A, Voss M, Alexaki VI, Morton L, Jahn SR, Katsoulis-Dimitriou K, Winzer S, Kollias G, Fischer T, Nedospasov SA, Dunay IR, Chavakis T, Müller AJ, Schraven B, Sperandio M, Dudeck A. (2021)
Directional mast cell degranulation of tumor necrosis factor into blood vessels primes neutrophil extravasation.
Immunity. 2021 Jan 15:S1074-7613(20)30545-8. doi: 10.1016/j.immuni.2020.12.017. Online ahead of print.
PMID: 33484643

2020

Immler R, Lange-Sperandio B, Steffen T, Beck H, Rohwedder I, Roth J, Napoli M, Hupel G, Pfister F, Popper B, Uhl B, Mannell H, Reichel CA, Vielhauer V, Scherberich J, Sperandio M, Pruenster M. (2020)
Extratubular Polymerized Uromodulin Induces Leukocyte Recruitment and Inflammation In Vivo.
Front Immunol. 2020 Dec 22;11:588245. doi: 10.3389/fimmu.2020.588245. eCollection 2020. PMID: 33414784

Preissner KT, Fischer S, Deindl E. (2020). Extracellular RNA as a Versatile DAMP and Alarm Signal That Influences Leukocyte Recruitment in Inflammation and Infection.
J Immunol. 2020 Dec 11:ji2000807. doi: 10.4049/jimmunol.2000807. Online ahead of print.
PMID: 33310871

Orosz A, Walzog B, Mócsai A. (2020). In Vivo Functions of Mouse Neutrophils Derived from HoxB8-Transduced Conditionally Immortalized Myeloid Progenitors.
J Immunol. 2020 Dec 11:ji2000807. doi: 10.4049/jimmunol.2000807. Online ahead of print.
PMID: 33310871

Lasch M, Kumaraswami K, Nasiscionyte S, Kircher S, van den Heuvel D, Meister S, Ishikawa-Ankerhold H, Deindl E. (2020). RNase A Treatment Interferes With Leukocyte Recruitment, Neutrophil Extracellular Trap Formation, and Angiogenesis in Ischemic Muscle Tissue. .
Front Physiol. 2020 Nov 6;11:576736. doi: 10.3389/fphys.2020.576736. eCollection 2020. PMID: 33240100

Rivière T, Bader A, Pogoda K, Walzog B, Maier-Begandt D. (2020) Structure and Emerging Functions of LRCH Proteins in Leukocyte Biology. Front Cell Dev Biol. 2020 Sep 22;8:584134. doi: 10.3389/fcell.2020.584134. eCollection 2020. PMID: 33072765 Review

Kameritsch P, Renkawitz J (2020) Principles of Leukocyte Migration Strategies. Trends in Cell Biology. doi: 10.1016/j.tcb.2020.06.007.

Deindl E, Quax PHA. Arteriogenesis and Therapeutic Angiogenesis in Its Multiple Aspects.Cells. 2020 Jun 10;9(6):E1439. doi: 10.3390/cells9061439. PMID: 32531915

Kopf A, Renkawitz J, Hauschild R, Girkontaite I, Tedford K, Merrin J, Thorn-Seshold O, Trauner D, Häcker H, Fischer KD, Kiermaier E, Sixt M. Microtubules control cellular shape and coherence in amoeboid migrating cells. J Cell Biol. 2020 Jun 1;219(6):e201907154. doi: 10.1083/jcb.201907154.

Elisabeth Deindl and Paul H. A. Quax. From Increased Fluid Shear Stress to Natural Bypass Growth. Int. J. Mol. Sci. 2020 May, 21, 3707; doi:10.3390/ijms21103707


Masgrau-Alsina S, Sperandio M, Rohwedder I. Neutrophil recruitment and intracellular vesicle transport: A short overview. Eur J Clin Invest. 2020 Jun;50(6):e13237. doi: 10.1111/eci.13237. Epub 2020 May 6. PMID: 32289185 Review.

Konda Kumaraswami, Natallia Salei, Sebastian Beck, Stephan Rambichler, Anna-Kristina Kluever, Manuel Lasch, Lisa Richter, Barbara U Schraml, Elisabeth Deindl. A Simple and Effective Flow Cytometry-Based Method for Identification and Quantification of Tissue Infiltrated Leukocyte Subpopulations in a Mouse Model of Peripheral Arterial Disease. Int J Mol Sci. 2020 May 19;21(10):E3593.
doi: 10.3390/ijms21103593.


Sitte S, Doehler D, Sperandio M, Marth JD, Voehringer D. The sialyltransferase ST3Gal-IV guides murine T-cell progenitors to the thymus. Blood Adv. 2020 May 12;4(9):1930-1941. doi: 10.1182/bloodadvances.2019001046. PMID: 32380539 Free PMC article.

Lasch M, Caballero Martinez A, Kumaraswami K, Ishikawa-Ankerhold H, Meister S, Deindl E (2020) Contribution of the potassium channels KV1.3 and KCa3.1 to smooth muscle cell proliferation in growing collateral arteries. Cells:9,913 doi:10.3390/cells9040913

Tamás Németh, Markus Sperandio and Attila Mócsai. Neutrophils as emerging therapeutic targets. Nat Rev Drug Discov (2020). https://doi.org/10.1038/s41573-019-0054-z

Athanasios Ziogas, Tomoki Maekawa, Johannes R. Wiessner, Thi Trang Le, David Sprott, Maria Troullinaki, Ales Neuwirth, Vasiliki Anastasopoulou, Sylvia Grossklaus, Kyoung-Jin Chung, Markus Sperandio, Triantafyllos Chavakis, George Hajishengallis and Vasileia Ismini Alexaki (2020). DHEA Inhibits Leukocyte Recruitment through Regulation of the Integrin Antagonist DEL-1. 2020/01/24/jimmun J Immunol published online 24 January 2020 

Salei N, Rambichler S, Salvermoser J, Papaioannou NE, Schuchert R, Pakalniškytė D, Li N, Marschner JA, Lichtnekert J, Stremmel C, Cernilogar FM, Salvermoser M, Walzog B, Straub T, Schotta G, Anders HJ, Schulz C, Schraml BU (2020). The Kidney Contains Ontogenetically Distinct Dendritic Cell and Macrophage Subtypes throughout Development That Differ in Their Inflammatory Properties. J Am Soc Nephrol. 2020 Jan 13. pii: ASN.2019040419. doi: 10.1681/ASN.2019040419 [Epub ahead of print]

2019

Markus Sperandio, Andreas Margraf und Roland Immler (2019) Funktionsreifung von Leukozyten und Blutplättchen im Rahmen der fetalen Entwicklung. Nova Acta Leopoldina NF Nr. 422, XXX–XXX (2019)

Manuel Lasch, Eike Christian Kleinert, Sarah Meister, Konda Kumaraswami, Judith-Irina Buchheim, Tobias Grantzow, Thomas Lautz, Sofia Salpisti, Silvia Fischer, Kerstin Troidl, Ingrid Fleming, Anna M. Randi, Markus Sperandio, Klaus T. Preissner, and Elisabeth Deindl (2019) Extracellular RNA released due to shear stress controls natural bypass growth by mediating mechanotransduction in mice.(Blood. 2019;134(17):1469-1479)

Anna-Kristina Kluever, Anna Braumandl, Silvia Fischer, Klaus T. Preissner and Elisabeth Deindl (2019) The Extraordinary Role of Extracellular RNA in Arteriogenesis, the Growth of Collateral Arteries. Int. J. Mol. Sci. 2019, 20, 6177; doi:10.3390/ijms20246177

Martin Wagner, Adrian Mahlmann, Elisabeth Deindl, Werner Zuschratter, Monika Riek-Burchardt, Sawa Kostin, Blerim Luani, Claudia Baer, Akram Youssef, Joerg Herold: Clinical improvement and enhanced collateral vessel growth after xenogenic monocyte transplantation. Am J Transl Res 2019;11(7):4063-4076.

Thulasingam S, Krishnasamy S, Raj C D, Lasch M, Vedantham S, Deindl E.(2019) Insulin Treatment Forces Arteriogenesis in Diabetes Mellitus by Upregulation of the Early Growth Response-1 (Egr-1) Pathway in Mice. Int J Mol Sci:20(13) doi: 10.3390/ijms20133320.

Beck S, Konda K, Salei N, Rambichler S, Braumandl A, Schraml BU, Deindl E. (2019). Flow cytometric analysis of leukocytes in soft tissue. Gefässchirurgie: https://doi.org/10.1007/s00772-019-0535-8

Mogessie, B., Zenner, H., & Renkawitz, J. (2019). Meeting report – Cell dynamics: organelle–cytoskeleton interface. J Cell Sci, 132(16), jcs236679. http://doi.org/10.1242/jcs.236679

Renkawitz J, Kopf A, Stopp J, de Vries I, Driscoll MK, Merrin J, Hauschild R, Welf ES, Danuser G, Fiolka R, Sixt S. Nuclear positioning facilitates amoeboid migration along the path of least resistance. Nature, April 03, 2019

Elsemüller AK, Tomalla V, Gärtner U, Troidl K, Jeratsch S, Graumann J, Baal N, Hackstein H, Lasch M, Deindl E, Preissner KT, Fischer S. (2019) Characterization of mast cell-derived rRNA-containing microvesicles and their inflammatory impact on endothelial cells. FASEB J:33(4):5457-5467 doi: 10.1096/fj.201801853RR

Klemm AH, Thomae AW, Wachal K, Dietzel S. Tracking Microscope Performance: A Workflow to Compare Point Spread Function Evaluations Over Time. Microsc Microanal (2019) Feb 6:1-6. doi: 10.1017/S1431927619000060

Ince, L., Weber, J., Scheiermann, C.(2019) Control of Leukocyte Trafficking by Stress-Associated Hormones. Frontiers in Immunology 2019 9:3143.

Margraf A, Nussbaum C, Sperandio M. Ontogeny of platelet function. Blood Adv. 692-703 (2019)

Krombach J, Hennel R, Brix N, Orth M, Schoetz U, Ernst A, Schuster J, Zuchtriegel G, Reichel CA, Bierschenk S, Sperandio M, Vogl T, Unkel S, Belka C, Lauber K. Priming anti-tumor immunity by radiotherapy: Dying tumor cell-derived DAMPs trigger endothelial cell activation and recruitment of myeloid cells. Oncoimmunology volume 8. Article: e1523097 (2019)

Cabeza-Cabrerizo M, van Blijswijk J, Wienert S, Heim D, Jenkins RP, Chakravarty P, Rogers N, Frederico B, Acton S, Beerling E, van Rheenen J, Clevers H, Schraml BU, Bajénoff M, Gerner M, Germain RN, Sahai E, Klauschen F, Reis E Sousa C. Tissue clonality of dendritic cell subsets and emergency DCpoiesis revealed by multicolor fate mapping of DC progenitors. Sci Immunol. 2019 Mar 1;4(33). pii: eaaw1941. doi: 10.1126/sciimmunol.aaw1941.

Papaioannou NE, Pasztoi M, Schraml BU. Understanding the Functional Properties of Neonatal Dendritic Cells: A Doorway to Enhance Vaccine Effectiveness? Front Immunol. 2019 Jan 10;9:3123. doi: 10.3389/fimmu.2018.03123. eCollection 2018. Review.

Ankush Jagtap PK, Müller M, Masiewicz P, von Bülow S, Hollmann NM, Chen PC, Simon B, Thomae AW, Becker PB, Hennig J. Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless. Nucleic Acids Res. 2019 Feb 26. pii: gkz125.

Weckbach LT, Grabmaier U, Uhl A, Gess S, Boehm F, Zehrer A, Pick R, Salvermoser M, Czermak T, Pircher J, Sorrelle N, Migliorini M, Strickland DK, Klingel K, Brinkmann V, Abu Abed U, Eriksson U, Massberg S, Brunner S, Walzog B (2019) Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis. J Exp Med 216: 350-368

2018

Kluever AK, Deindl E. (2018) Extracellular RNA, a Potential Drug Target for Alleviating Atherosclerosis, Ischemia/Reperfusion Injury and Organ Transplantation. Curr Pharm Biotechnol:19(15):1189-1195 doi: 10.2174/1389201020666190102150610

Kluever AK, Deindl E. (2018) Extracellular Nucleic Acids in Health and Disease. Curr Pharm Biotechnol:19(15):1180-1181 doi: 10.2174/138920101915190125142421

Deindl E. (2018) Midkine controls natural bypass growth by regulating the bioavailability of VEGF. In: Atlas of Science; http://atlasofscience.org

Vedantham S, Kluever AK, Deindl E. (2018) Is there a Chance to Promote Arteriogenesis by DPP4 Inhibitors Even in Type 2 Diabetes? A Critical Review. Cells doi: 10.3390/cells7100181

Weckbach LT, Preissner KT, Deindl E. (2018) The Role of Midkine in Arteriogenesis Involving Mechanosensing, Endothelial Cell Proliferation, and Vasodilation. Int J Mol Scidoi: 10.3390/ijms19092559

Lasch M, Nekolla K, Klemm AH, Buchheim JI, Pohl U, Dietzel S, Deindl E.(2018) Estimating hemodynamic shear stress in murine peripheral collateral arteries by two-photon line scanning. Mol Cell Biochem 453(1-2):41-51 doi: 10.1007/s11010-018-3430-9

Buchheim JI, Hoskyns S, Moser D, Han B, Deindl E, Hörl M, Biere K, Feuerecker M, Schelling G, Choukèr A. (2018) Oxidative burst and Dectin-1-triggered phagocytosis affected by norepinephrine and endocannabinoids: implications for fungal clearance under stress. Int Immunol:30(2):79-89

Lautz T, Lasch M, Borgolte J, Troidl K, Pagel JI, Caballero-Martinez A, Kleinert EC, Walzog B, Deindl E. (2018) Midkine Controls Arteriogenesis by Regulating the Bioavailability of Vascular Endothelial Growth Factor A and the Expression of Nitric Oxide Synthase 1 and 3. EBioMedicine:27:237-246

Renkawitz J, Reversat A, Leithner A, Merrin J, Sixt M. (2018) Micro-engineered ‘Pillar Forests’ to Study Cell Migration in Complex but Controlled 3D Environments. Methods in Cell Biology, 147:79-91

Hons M, Kopf A, Hauschild R, Leithner A, Gaertner F, Abe J, Renkawitz J, Stein JV, Sixt M. (2018) Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells. Nat Immunol. 19:606-16.

Leithner A, Renkawitz J, De Vries I, Hauschild R, Häcker H, Sixt M. (2018) Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration. Eur J Immunol. 48:1074-77.

Frick C, Dettinger P, Renkawitz J, Jauch A, Berger CT, Recher M, Schroeder T, Mehling M. (2018) Nano-scale microfluidics to study 3D chemotaxis at the single cell level. PLoS One. 13:e0198330.

He, W., Holtkamp, S., Hergenhan, S., Kraus, K., de Juan, A., Weber, J., Bradfield, P., Grenier, J., Pelletier, J., Druzd, D., Chen, C., Ince, L., Bierschenk, S., Pick, R., Sperandio, M., Scheiermann, C. (2018) Circadian Expression of Migratory Factors Establishes Lineage-Specific Signatures that Guide the Homing of Leukocyte Subsets to Tissues. Immunity. 2018 49: 1–16.

Moretti FA., Klapproth S., Ruppert R., Margraf A., Weber J., Pick R., Scheiermann C., Sperandio M., Fässler R., Moser M. (2018) Differential requirement of kindlin-3 for T-cell progenitor homing to the non-vascularized and vascularized thymus. eLIFE. 2018 7:e35816.

Scheiermann, C., Gibbs, J., Ince, L., & Loudon, A. Clocking in to immunity. Nature Reviews Immunology.(2018) 18:423–437. Cover

Winter, C., Silvestre-Roig, C., Ortega-Gomez, A., Lemnitzer, P., Poelman, H., Schumski, A., Winter, J., Drechsler, M., de Jong, R., Immler, R., Sperandio, M., Hristob, M., Zeller, T., Nicolaes, G., Weber, C., Viola, J., Hidalgo, A., Scheiermann, C., Soehnlein, O. (2018) Chrono-pharmacologial Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis. Cell Metabolism. 2018 28:175–182.

Salvermoser J, van Blijswijk J, Papaioannou NE, Rambichler S, Pasztoi M, Pakalniškytė D, Rogers NC, Keppler SJ, Straub T, Reis e Sousa C, Schraml BU. (2018) Clec9a-Mediated Ablation of Conventional Dendritic Cells Suggests a Lymphoid Path to Generating Dendritic Cells In Vivo. Front Immunol 9, 563–15. doi:10.3389/fimmu.2018.00699

C. Stremmel, R. Schuchert, F. Wagner, R. Thaler, T. Weinberger, R. Pick, E. Mass, H. C. Ishikawa-Ankerhold, A. Margraf, S. Hutter, R. Vagnozzi, S. Klapproth, J. Frampton, S. Yona, C. Scheiermann, J. D. Molkentin, U. Jeschke, M. Moser, M. Sperandio, S. Massberg, F. Geissmann & C. Schulz. Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nature Communications volume 9, Article number: 75 (2018)

Bromberger T, Klapproth S, Rohwedder I, Zhu L, Mittmann L, Reichel CA, Sperandio M, Qin J, Moser M. Direct Rap1/Talin1 interaction regulates platelet and neutrophil integrin activity in mice. Blood (2018) 132(26):2754-2762.

Immler R, Simon SI, Sperandio M. Calcium signalling and related ion channels in neutrophil recruitment and function. Eur J Clin Invest. (2018) 48 Suppl 2:e12964.

Tseng HY, Samarelli AV, Kammerer P, Scholze S, Ziegler T, Immler R, Zent R, Sperandio M, Sanders CR, Fässler R, Böttcher RT. LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow. J Cell Sci.(2018) Nov 21;131(22)

Kurz ARM, Catz SD, Sperandio M. Noncanonical Hippo Signalling in the Regulation of Leukocyte Function. Trends Immunol. (2018)39(8):656-669.

Sperandio M. CEP: a new β(2) integrin ligand in inflamed tissue. Blood. (2018)132(1):4-5.

Suarez-Martinez AD, Bierschenk S, Huang K, Kaplan D, Bayer CL, Meadows SM, Sperandio M, Murfee WL. A Novel ex vivo Mouse Mesometrium Culture Model for Investigating Angiogenesis in Microvascular Networks. J Vasc Res. (2018);55(3):125-135.

Vinketova К, Karagyozov I, Koleva V, Hristov M, Mourdjeva M, Sperandio M, Oreshkova T. Progesterone and cyclic adenosine monophosphate down-regulate CD90 in the stromal cells of human decidua. In vitro evidence and in situ findings. Am J Reprod Immunol.(2018)80(5):e13043.

Ye Y, Vattai A, Ditsch N, Kuhn C, Rahmeh M, Mahner S, Ripphahn M, Immler R, Sperandio M, Jeschke U, von Schönfeldt V. Prostaglandin E(2) receptor 3 signaling is induced in placentas with unexplained recurrent pregnancy losses. Endocr Connect.(2018)7(5):749-761.

Salvermoser M, Begandt D, Alon R, Walzog B (2018) Nuclear Deformation During Neutrophil Migration at Sites of Inflammation. Front Immunol 9: 2680

Stocker TJ, Pircher J, Skenderi A, Ehrlich A, Eberle C, Megens RTA, Petzold T, Zhang Z, Walzog B, Muller-Taubenberger A, Weber C, Massberg S, Ishikawa-Ankerhold H, Schulz C (2018) The Actin Regulator Coronin-1A Modulates Platelet Shape Change and Consolidates Arterial Thrombosis. Thromb Haemost 118: 2098-2111

Zehrer A, Pick R, Salvermoser M, Boda A, Miller M, Stark K, Weckbach LT, Walzog B, Begandt D. (2018) A Fundamental Role of Myh9 for Neutrophil Migration in Innate Immunity. J Immunol. 201:1748-64.

Thome S, Begandt D, Pick R, Salvermoser M, Walzog B. (2018) Intracellular beta2 integrin (CD11/CD18) interacting partners in neutrophil trafficking. Eur J Clin Invest.e12966.

Souza-Almeida G, D'Avila H, Almeida PE, Luna-Gomes T, Liechocki S, Walzog B, Hepper I, Castro-Faria-Neto HC, Bozza PT, Bandeira-Melo C, Maya-Monteiro CM. (2018) Leptin Mediates In Vivo Neutrophil Migration: Involvement of Tumor Necrosis Factor-Alpha and CXCL1. Front Immunol. 9:111.

Salvermoser M, Pick R, Weckbach LT, Zehrer A, Lohr P, Drechsler M, Sperandio M, Soehnlein O, Walzog B. (2018) Myosin 1f is specifically required for neutrophil migration in 3D environments during acute inflammation. Blood. 131:1887-98.

Rami M, Guillamat-Prats R, Rinne P, Salvermoser M, Ring L, Bianchini M, Blanchet X, Megens RTA, Doring Y, Walzog B, Soehnlein O, Weber C, Faussner A, Steffens S. (2018) Chronic Intake of the Selective Serotonin Reuptake Inhibitor Fluoxetine Enhances Atherosclerosis. Arterioscler Thromb Vasc Biol. 38:1007-19.

Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C. (2018) Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation. Nat Commun. 9:1523.

Goncalves-de-Albuquerque CF, Rohwedder I, Silva AR, Ferreira AS, Kurz ARM, Cougoule C, Klapproth S, Eggersmann T, Silva JD, de Oliveira GP, Capelozzi VL, Schlesinger GG, Costa ER, Estrela Marins RCE, Mocsai A, Maridonneau-Parini I, Walzog B, Macedo Rocco PR, Sperandio M, de Castro-Faria-Neto HC. (2018) The Yin and Yang of Tyrosine Kinase Inhibition During Experimental Polymicrobial Sepsis. Front Immunol. 9:901.

Novak M, Polak B, Simunić J, Boban Z, Kuzmić B, Thomae AW, Tolić IM, Pavin N. The mitotic spindle is chiral due to torques within microtubule bundles. Nat Commun. 2018 Sep 3;9(1):3571.

Anselm E, Thomae AW, Jeyaprakash AA, Heun P. Oligomerization of Drosophila Nucleoplasmin-Like Protein is required for its centromere localization. Nucleic Acids Res. 2018 Nov 30;46(21):11274-11286.

2017

Gerland TA, Sun B, Smialowski P, Lukacs A, Thomae AW, Imhof A. The Drosophila speciation factor HMR localizes to genomic insulator sites. PLoS One. 2017 Feb 16;12(2):e0171798.

Lademann CA, Renkawitz J, Pfander B, Jentsch S. (2017) INO80-C removes H2A.Z to promote presynaptic filament formation during homologous recombination. Cell Reports. 9:1294-1303.

Druzd, D., Matveeva, O., Ince, L., Harrison, U., He, W., Schmal, C., Herzel, H., Tsang, A., Kawakami, N., Leliavski, A., Uhl, U., Yao, L., Sander, L., Chen, C., Kraus, K., de Juan, A., Hergenhan, S., Ehlers, M., Koletzko, B., Haas, R., Solbach, W., Oster, H. and Scheiermann, C. Lymphocyte circadian clocks control lymph node trafficking and adaptive immune responses. Immunity. 2017 46:120-132. Cover & Best of Immunity 2017 (http://info.cell.com/best-of-immunity-2017)

Pakalniškytė D, Schraml BU. Tissue-Specific Diversity and Functions of Conventional Dendritic Cells. In: Vol 134. Advances in Immunology. Elsevier (2017) 89-135.

W. H. Yang, D. M. Heithoff, P. V. Aziz, M. Sperandio, V. Nizet, M. J. Mahan, and J. D. Marth. Recurrent infection progressively disables host protection against intestinal inflammation. Science 358 (6370), 2017.

D. Begandt, S. Thome, M. Sperandio, and B. Walzog. How neutrophils resist shear stress at blood vessel walls: molecular mechanisms, subcellular structures, and cell-cell interactions. J Leukoc.Biol 102 (3):699-709, 2017.

A. Margraf, C. Nussbaum, I. Rohwedder, S. Klapproth, A. R. M. Kurz, A. Florian, V. Wiebking, J. Pircher, M. Pruenster, R. Immler, S. Dietzel, L. Kremer, F. Kiefer, M. Moser, A. W. Flemmer, E. Quackenbush, U. H. von Andrian, and M. Sperandio. Maturation of Platelet Function During Murine Fetal Development In Vivo. Arterioscler Thromb Vasc Biol 37 (6):1076-1086, 2017.

Uhl, S. Hirn, R. Immler, K. Mildner, L. Mockl, M. Sperandio, C. Brauchle, C. A. Reichel, D. Zeuschner, and F. Krombach. The Endothelial Glycocalyx Controls Interactions of Quantum Dots with the Endothelium and Their Translocation across the Blood-Tissue Border. ACS Nano. 11 (2):1498-1508, 2017.

Samereier M, Schleicher M, Roth H, Brechtefeld D, Walzog B, Muller-Taubenberger A. (2017) EB1 contributes to proper front-to-back polarity in neutrophil-like HL-60 cells. Eur J Cell Biol. 96:143-53.

Roth H, Samereier M, Begandt D, Pick R, Salvermoser M, Brechtefeld D, Schleicher M, Walzog B, Muller-Taubenberger A. (2017) Filamin A promotes efficient migration and phagocytosis of neutrophil-like HL-60 cells. Eur J Cell Biol. 96:553-66.

Pick R, Begandt D, Stocker TJ, Salvermoser M, Thome S, Bottcher RT, Montanez E, Harrison U, Forne I, Khandoga AG, Coletti R, Weckbach LT, Brechtefeld D, Haas R, Imhof A, Massberg S, Sperandio M, Walzog B. (2017) Coronin 1A, a novel player in integrin biology, controls neutrophil trafficking in innate immunity. Blood. 130:847-58.

Abdel Malik R, Zippel N, Fromel T, Heidler J, Zukunft S, Walzog B, Ansari N, Pampaloni F, Wingert S, Rieger MA, Wittig I, Fisslthaler B, Fleming I. (2017) AMP-Activated Protein Kinase alpha2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1alpha and a Network of Proteins Affecting Metabolism and Apoptosis. Circ Res. 120:99-109.